土志涵

土志涵

职称/头衔：讲师

E-mail：zhtu@hainanu.edu.cn；17321365091@163.com

● 个人简介

广东海洋大学学士（2012-2016），上海海洋大学硕士/博士/博士后（2016-2024），2024年8月加入海南大学海洋科学与工程学院。本人主要从事海洋生态生理、环境毒理研究，从细胞、免疫、生理和行为生态等不同层次上系统探究海洋污染物（噪声污染、微纳米塑料、纳米颗粒和重金属等）胁迫下水生动物的生态生理适应过程和机制。先后承担上海市外国专家项目和各重点实验室课题，近年来以第一（共一）作者发表SCI论文10篇。获2023年上海市大学生生命科学竞赛指导老师三等奖，2023年全国大学生生命科学竞赛指导教师三等奖。

●研究方向

1） 环境应激与水生毒理学过程与机制； 

2） 珊瑚礁物种响应多重环境变化的适应和调控机制

●科研项目与课题

1. 上海市外国专家项目：生物冠在纳米颗粒对底栖无脊椎动物毒性中的调节作用 (23WZ2502800)，主持。

2. 广西北部湾海洋生物多样性养护重点实验室开放课题：升温背景下季节性海水酸化和缺氧对北部湾牡蛎多样性的复合效应 (2023KA04)主持。

3. 烟台市特色海洋生物开发利用工程实验室开放课题：高温和缺氧对长牡蛎 (Crassostrea gigas)繁殖期的生理生态效应，主持。

4. 浙江海洋大学海洋科学浙江省一流学科建设开放课题：浙江三门湾海域微塑料污染分布特征调查研究 (OFMS009)，主持。

● 论文与专著

(1) Amouri, R.E.#, Tu, Z.#, Abo-Raya, M.H., Pang, X., Hu, M., Wang, Y. (2025). Nano-TiO2 impairs the health of crabs Charybdis japonica under warming conditions through waterborne and dietary exposures. Journal of Hazardous Materials, 487, 137092. https://doi.org/10.1016/j.jhazmat.2025.137092

(2) Tu, Z., Tang, L., Shen, H., Hu, M., Chen, F., Wang, X., Abo-Raya, M.H., Wang, Y. (2025). Molecular insights into the physiological impact of low-frequency noise on sea slug Onchidium reevesii: Activation of p53 signaling and oxidative stress response. Journal of Environmental Management, 373, 123481. https://doi.org/10.1016/j.jenvman.2024.123481

(3) Chen, L.#, Tu, Z.#, Zhong, Z., Wei, S., Hu, M., Wang, Y. (2025). Differential effects of polyvinyl chloride microplastics and kaolin particles on gut immunity of mussels at environmental concentrations. Journal of Hazardous Materials, 484, 136711. https://doi.org/10.1016/j.jhazmat.2024.136711

(4) Amouri, R.E.#, Tu, Z.#, Abo-Raya, M. H., Wang, X., Shi, Y., Hu, M., Wang, Y. (2024). Nano-TiO2 and elevated temperature impair intestinal health in crabs via a mussel-based food chain. Environmental Science: Nano, 11(12), 4698-4716. https://doi.org/10.1039/D4EN00657G

(5) Tu, Z., Tang, L., Khan, F. U., Hu, M., Shen, H., Wang, Y. (2024). Low-frequency noise impairs righting reflex behaviour by disrupting central nervous system in the sea slug Onchidium reevesii. Science of the Total Environment, 918,170552. https://doi.org/10.1016/j.scitotenv.2024.170552.

(6) Tu, Z., Tang, L., Khan, F. U., Hu, M., Shen, H., Wang, Y. (2024). Low-frequency noise aggravates the toxicity of cadmium in sea slug Onchdium reevesii. Science of the Total Environment, 912,169558. https://doi.org/10.1016/j.scitotenv.2023.169558.

(7) Tu, Z., Tang, L., Abo-Raya, M. H., Sun, M., Shen, H., Wang, Y. (2024). Cloning and characterization of heat shock transcription factor 1 and its functional role for Hsp70 production in the sea slug Onchidium reevesii. Gene, 893, 147945. https://doi.org/10.10 16/j.gene.2023.147945.

(8) Tu, Z., Li, C., Jia, J., Shen, H. (2022). Behavioral and physiological responses of sea slug (Onchidium reevesii) to low-Frequency noise. Journal of Ocean University of China, 21(6), 1607-1614. https://doi.org/10.1007/s11802-022-5041-z.

(9) Tu, Z., Tang, L., Yang, H., Zhang, X., Jiang, C., Shen, H. (2022). Effect of low-frequency noise on the survival rate and immunity of infected Vibrio parahaemolyticus sea slug (Onchidium reevesii). Fish & Shellfish Immunology, 126, 227-236.  https://doi.org/10.1016/j.fsi.2022.05.045.

(10) Tu, Z., Tang, L., Zhang, X., Jia, J., Shen, H. (2021). Transcriptome analysis of the central nervous system of sea slug (Onchidium reevesii) exposed to low-frequency noise. Frontiers in Marine Science, 8, 807489. https://doi.org/10.3389/fmars.2021.807489.